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Original Article | J Health Care and Research. 2022 May 24;3(1):16-30 | DOI: 10.36502/2022/hcr.6207

Diagnosis of Thyroid Malignancy using Levels of Chemical Element Contents in Nodular Tissue

Author(s): Vladimir Zaichick*

Abstract

Introduction: Thyroid benign (TBN) and malignant (TMN) nodules are a common thyroid lesion. The differentiation of TMN often remains a clinical challenge and further improvements of TMN diagnostic accuracy are warranted. The aim of present study was to evaluate possibilities of using differences in chemical elements (ChEs) contents in nodular tissue for diagnosis of thyroid malignancy.
Methods: Contents of ChEs such as aluminum (Al), boron (B), barium (Ba), calcium (Ca), chlorine (Cl), coper (Cu), iron (Fe), iodine (I), potassium (K), lithium (Li), magnesium (Mg), manganese (Mn), sodium (Na), phosphorus (P), sulfur (S), silicon (Si), strontium (Sr), vanadium (V), and zinc (Zn) were prospectively evaluated in “normal” thyroid (NT) of 105 individuals as well as in nodular tissue of thyroids with TBN (79 patients) and to TMN (41 patients). Measurements were performed using a combination of non-destructive and destructive methods: instrumental neutron activation analysis with high resolution spectrometry of short-lived radionuclides and inductively coupled plasma atomic emission spectrometry.
Results: It was observed that in TMN tissue the mean mass fraction of I was lower while the mean mass fractions of K, Mg, and P were higher than in both NT and TBN groups of samples. It was demonstrated that I content is nodular tissue is the most informative parameter for the diagnosis of thyroid malignancy. It was found that “Sensitivity”, “Specificity” and “Accuracy” of TMN identification using the I level in the needle biopsy of affected thyroid tissue was significantly higher than that using US examination and cytological test of fine needle aspiration biopsy.
Conclusions: It was concluded that determination of the I level in a needle biopsy of TNs using non-destructive instrumental analytical method is a fast, reliable, and very informative diagnostic tool that can be successfully used as an additional test of thyroid malignancy identification.

Original Article | J Health Care and Research. 2022 Apr 25;3(1):11-15 | DOI: 10.36502/2022/hcr.6206

Retrospective Cross-Sectional Analysis of COVID-19 Patients in a Local Hospital during Delta Surge

Author(s): Bahaar Kaur Muhar^*, Hillary Chu, Norah Zhou

Abstract

Many community members believe the vaccine is not effective against COVID-19 and that local hospitals are full of vaccinated patients with severe COVID-19. Furthermore, they feel national figures do not reflect local numbers. We aimed to analyze the profile of COVID-19 patients in our local community hospital in Sacramento, California to see if indeed most COVID-19 hospitalized patients are vaccinated. This is a retrospective cross-sectional study of COVID-19 patients that were admitted to a community hospital on August 26, 2021, during the delta variant surge. We analyzed the profile of patients in the hospital who had a positive COVID-19 test by PCR. A total of 96 COVID-19 patients were studied of which 20 are vaccinated and 76 are unvaccinated. The average age of hospitalized vaccinated patients with COVID-19 is 69 while unvaccinated patients is 52.6. Additionally, 24 patients were on high flow oxygen with only 3 of them being fully vaccinated. There are 26 patients in the ICU with COVID-19 of which only 3 are fully vaccinated. 21 of these ICU patients are on mechanical ventilation with only 2 being fully vaccinated. Our data is consistent with national trends. While breakthrough infections are inevitable, analysis shows that the elderly population is most significantly impacted. However, breakthrough infections tend to also be less severe. Importantly, the unvaccinated population with COVID-19 disease and hospitalization tend to be of younger age. Altogether, this data from our local hospital highlights and emphasizes the need for our community to be fully vaccinated to prevent COVID-19 disease and hospitalizations.

Review Article | J Health Care and Research. 2022 Feb 10;3(1):1-6 | DOI: 10.36502/2022/hcr.6204

Robotic Surgery in Total Hip Replacement in Obesity

Author(s): Mohammed Almashahedi^*, Wasim Khan, Stephen McDonnell

Abstract

Total hip replacement is one of the most successful orthopaedic operation of recent time. The outcomes of THR may be influenced by several factors including patient demographics, surgical technique and implant features. One of the most important surgeon-controlled factors is component positioning. Surgical positioning of the acetabular cup and femoral prosthesis remains fundamental to obtaining accurate implant fit and prevent hip dislocation or impingement. Different categories of robotic assistance have been established during the previous years and all of the technologies target accuracy and reliability to reduce complications, and enhance clinical outcomes.

In this article, we discuss the advantages and difficulties of robotic total hip replacement in obese patient and provide the recent scientific evidence from the literatures.

Original Article | J Health Care and Research. 2021 Nov 15;2(3):170-75 | DOI: 10.36502/2021/hcr.6203

Relationship Between Tongue Strength and Dysphagia Symptoms in Japanese Older Adults in Need of Care

Author(s): Morisaki Naoko^*

Abstract

Purpose: The purpose of this study was to measure the tongue pressure of older adults who require nursing care and to clarify the relationship between dysphagia symptoms and tongue strength.
Methods: The participants were Japanese older adults (age: ≥ 65 years) in need of care who were able to communicate with others and agreed to participate in the study. Tongue pressure was measured using TPM-01, a tongue pressure measuring instrument. The Dysphagia Risk Assessment for Community-Dwelling Elderly was used to assess dysphagia. The association between tongue pressure and 12 dysphagia symptoms was analyzed using a one-way analysis of variance.
Results: The average tongue pressure was 23.22 ± 9.9 kPa. Tongue pressure was significantly associated with occasional food spillage from the mouth and sputum formation in the throat during meals or after eating or drinking (p < 0.05).
Conclusions: Decreased tongue strength should be suspected in older adults with food spillage from the mouth or sputum formation in the throat during meals.

Review Article | J Health Care and Research. 2021 Sept 27;2(3):146-52 | DOI: 10.36502/2021/hcr.6200

Damage in Dentistry

Author(s): Siniša Franjić^*

Abstract

Dentistry is one of the clinical disciplines that is closely related to medicine, but also to the technology of making various devices and placing artificial materials that compensate and/or upgrade lost teeth and surrounding structures. Dentistry is also medically responsible for the treatment of patients with diseases of the oral cavity. The main task of dentistry is healthy teeth and oral cavity, ie their preservation and treatment of damaged teeth. Caries is the most common dental disease, and is caused by the multiplication of bacteria inside the oral cavity due to lack of oral hygiene. If not treated in time, caries penetrates deeper tooth structures and destroys them which leading to tooth decay. The most common symptoms of caries are tooth sensitivity and toothache. If these symptoms occur, it is necessary to perform an examination at the dentist in order to prevent the disease immediately at the beginning and to avoid significant consequences for dental health. If caries is not treated in time, there is a high chance that irreparable damage will occur to the teeth and tooth tissue, which can ultimately result in the loss of one or more teeth.