Asploro Journal of Biomedical and Clinical Case Reports

About Asploro Journal of Biomedical and Clinical Case Reports [ASJBCCR]

Asploro Journal of Biomedical and Clinical Case Reports is an open-access, peer-reviewed journal with the aim of advancing global health outcomes by sharing clinical knowledge through case reports. These reports serve as a valuable tool for conveying important best practices and each case report published adds to the body of medical knowledge.

Case reports are the foundation of research writing in the healthcare field, providing a fundamental study design. They offer valuable contributions to medical knowledge and have educational significance, as well as the potential to highlight the need for changes in clinical practices or diagnostic/prognostic methods. At Asploro Journal of Biomedical and Clinical Case Reports, we welcome submissions that carry important clinical messages and will consider each submission carefully.

Asploro Journal of Biomedical and Clinical Case Reports is committed to publishing original case reports, clinical images, procedural videos, original research related to case reports, and short communications from all areas of Medicine, Nursing, Dentistry, and Veterinary Science. Our journal welcomes submissions from a wide range of health sciences, including biochemistry, microbiology, developmental biology, cell biology, genetics, immunology, molecular biology, structural biology, translational medicine, protein science, clinical epigenetics, clinical trials, clinical pharmacology, physiology, neuroscience, and more. Our goal is to expand the field of general medical knowledge and provide a platform for sharing valuable clinical insights.

To submit your manuscript to Asploro Journal of Biomedical and Clinical Case Reports, kindly send it as an e-mail attachment to the Editorial Office at editor.biomed@asploro.com. We look forward to receiving your submission and the opportunity to review and potentially publish your work.

There are several reasons why you may want to consider publishing with Asploro Journal of Biomedical and Clinical Case Reports:

Open Access: Our journal is an open-access journal, which means that all articles are freely available to the public, increasing the visibility and impact of your work.

Peer Review: All articles published in our journal undergo rigorous peer review to ensure the highest quality of content and accuracy.

Global Reach: Our journal has a global reach, providing authors with the opportunity to share their work with a large and diverse audience.

Rapid Publication: Our journal has a fast publication process, allowing authors to share their work with the world in a timely manner.

Wide Range of Topics: Our journal covers a wide range of topics within the field of biomedical and clinical case reports, offering authors the opportunity to publish their work in a relevant and specific area.

Contribution to Medical Knowledge: Publishing in our journal is a way to contribute to the advancement of medical knowledge and improve global health outcomes.

Interdisciplinary Platform: Our journal is an interdisciplinary platform, providing authors with the opportunity to engage with researchers and practitioners from diverse backgrounds and fields.

Most Recent Articles

Stroke Secondary to Fibromuscular Dysplasia

Case Report | Asp Biomed Clin Case Rep. 2023 Jun 27;6(2):156-60 | DOI: 10.36502/2023/ASJBCCR.6308

Anesthesia Management of a Patient with Papillary Thyroid Carcinoma Recurrence and Metastasis to the Right Atrium and Superior Vena Cava: A Case Report

Author(s): Xinghui Xiong^*

Abstract

Postoperative recurrence and metastasis of papillary thyroid carcinoma (PTC) to the superior vena cava (SVC) and right atrium (RA) are rare. The application of Extracorporeal Jugular-femoral Vein Bypass and anesthesia management for SVC reconstruction in this rare situation holds instructive significance. In this case, we describe the successful anesthesia management of a patient with multiple tumor thrombi due to postoperative recurrence of PTC. The diagnosis was based on computed tomography of the chest and blood vessels, revealing three-dimensional SVC, postoperative recurrence of PTC, and multiple tumor thrombi in the internal jugular vein (IJV), subclavian vein, brachiocephalic vein, SVC, and RA. An experienced multidisciplinary team was established, and a detailed plan was made for respiration and circulation support, with cardiopulmonary bypass on standby.

Case Report | Asp Biomed Clin Case Rep. 2023 Jun 26;6(2):138-45 | DOI: 10.36502/2023/ASJBCCR.6306

Stroke Sec ondary to Fibromuscular Dysplasia

Author(s): Ashwin Sidhu^ID^*, Harrison Chu^ID

Abstract

FMD is a rare systemic vascular disease characterized by abnormal cell proliferation in the artery walls, leading to artery narrowing, twisting, or bulging. It commonly affects the carotid and renal arteries and can result in renal diseases and stroke. This paper presents a case study of a 39-year-old unhoused female patient who experienced a stroke secondary to fibromuscular dysplasia (FMD) and left ventricular thrombus. The patient presented with asymmetric movement of the extremities and psychosis, so intoxication was initially suspected. However, further examination revealed facial asymmetry and motor weakness. CT scans showed a left anterior cerebral artery infarction and irregular contour of the cervical internal carotid arteries, consistent with FMD and carotid thrombus. Management involved stabilizing the patient, providing supportive treatment, and controlling blood pressure. Thrombolytic therapy was not administered due to the time elapsed since symptom onset. The patient was started on anticoagulation for the carotid plaque and left ventricular thrombus. A transthoracic echocardiogram revealed a large left ventricular thrombus and left atrial enlargement, and the patient was started on heart failure medications.
FMD and left ventricular thrombus are not directly related, but FMD can contribute to thrombus development through its impact on the cardiovascular system, including hypertension, arterial wall damage, aneurysm development, or dissection. Treatment for FMD may involve medication, observation, or surgical interventions like angioplasty and stenting. Anticoagulation therapy is essential for managing the left ventricular thrombus.
This case highlights the importance of early diagnosis and treatment of FMD to prevent complications such as stroke. It is important to consider FMD in the diagnosis of younger patients with a stroke, especially those with a history of hypertension, substance abuse, or other risk factors. Further research is needed to better understand the relationship between FMD and stroke and to optimize treatment strategies for these patients.

Case Report | Asp Biomed Clin Case Rep. 2023 Jun 24;6(2):130-37 | DOI: 10.36502/2023/ASJBCCR.6305

Maintained Renal Function by Blood Pressure Control in Patient with Diabetic Kidney Disease (DKD)

Author(s): Hiroshi Bando^ID*, Noboru Iwatsuki, Masaki Okada, Tomoya Ogawa, Kazuki Sakamoto

Abstract

The case involves a 74-year-old male with type 2 diabetes (T2D), hypertension, dyslipidemia, and diabetic kidney disease (DKD) at nephropathy stage G3b. He has been receiving treatment with insulin and anti-hypertensive agents (AHAs). In July 2021, his HbA1c was elevated to 7.9%. As a result, the extent of his low carbohydrate diet (LCD) was increased, and insulin doses were raised. The AHAs were changed from Olmesartan to Valsartan/Amlodipine, and Irbesartan/Amlodipine until 2023. By January 2023, his HbA1c had decreased to 6.8%, and his eGFR (CKD-EPI) had remained stable at 34-48 mL/min/1.73/m² for 4 years. A recent study demonstrated clinical improvement in renal function through continuous LCD in patients with DKD.

Case Report | Asp Biomed Clin Case Rep. 2023 Jun 13;6(2):124-29 | DOI: 10.36502/2023/ASJBCCR.6304

Anesthetic Management of an Unusual Case of Severe Pulmonary Hypertensive

Author(s): Peipei Sun

Abstract

The perioperative management of pulmonary hypertension continues to be a great challenge for anesthesiologists. Among the various types of pulmonary hypertension, pulmonary hypertension associated with left heart disease is the most common, while pulmonary hypertensive crisis is one of the causes of perioperative mortality in these patients. We present the case of a 54-year-old female with severe valvular heart disease complicated by severe pulmonary hypertension and massive hemothorax, who underwent emergency exploratory thoracotomy, mitral valve replacement, and tricuspid valvuloplasty. The patient was in critical condition and suspected to have a pulmonary hypertension crisis. The rationale for this case report is to learn about the anesthetic management of patients with severe pulmonary hypertension.

Case Report | Asp Biomed Clin Case Rep. 2023 Jun 12;6(2):116-23 | DOI: 10.36502/2023/ASJBCCR.6303

Relieved Depressive State and Glycemic Control in Type 2 Diabetes (T2D) Patient Treated by Imeglimin (Twymeeg)

Author(s): Masaki Okada, Hiroshi Bando^ID*, Noboru Iwatsuki, Kazuki Sakamoto, Tomoya Ogawa

Abstract

The patient is a 66-year-old female being treated for hypertension. She developed a cerebral vascular accident (CVA) in October 2019, and was subsequently diagnosed with type 2 diabetes (T2D) due to an HbA1c level of 9.8%. She began a low carbohydrate diet (LCD) and started taking oral hypoglycemic agents (OHAs) such as metformin and linagliptin. From July 2021, she occasionally experienced anxiety and palpitations, leading to a diagnosis of reactive depression (adjustment disorder). Despite treatment with etizolam as needed, these symptoms persisted. In December 2022, due to an increase in HbA1c levels to 7.7%, metformin was switched to imeglimin (Twymeeg). By April 2023, her HbA1c had decreased to 6.9%, and she reported a sustained sense of well-being without psychosomatic symptoms.