Asploro Journal of Biomedical and Clinical Case Reports
Asploro Journal of Biomedical and Clinical Case Reports
Asploro Journal of Biomedical and Clinical Case Reports [ISSN: 2582-0370]
ISSN: 2582-0370 | Volume-5
PubMed NLM ID: 9918335073606676

About Asploro Journal of Biomedical and Clinical Case Reports [ASJBCCR]

Asploro Journal of Biomedical and Clinical Case Reports is an open access, peer-reviewed journal which mainly aims to directly improve global health outcomes and share clinical knowledge using case reports to convey important best practice messages. Each case report published in this journal adds valuable new information to medical knowledge.

Case Reports are the first piece of research writing in the health field and represent the most basic type of study design. They make a contribution to health knowledge and have educational value or highlight the need for a change in clinical practice or diagnostic/prognostic approaches. If your submission has an important clinical message we would like to read it!

ASJBCCR welcomes original case reports that expands the field of general medical knowledge, clinical images, procedural videos, original research relating to case reports, and short communications from all areas of Medicine, Nursing, Dentistry, and Veterinary Science. Case reports can span the full spectrum of health sciences in the broadest sense, including biochemistry, microbiology, developmental biology, cell biology, genetics, immunology, molecular biology, structural biology, translational medicine, protein science, clinical epigenetics, clinical trials, clinical pharmacology, physiology, neuroscience, etc.,

Submit manuscript as an e-mail attachment to the Editorial Office at

Why Publish With Us

  • All the published articles are open access which means it’s free to access from anywhere in the world.
  • We offer fast publication while providing rigorous peer review to maintain the integrity of information.
  • Each article will be published under a Creative Commons license and authors are the copyright holder.
  • We are committed to the highest standards of peer review.
  • We’re proud of the impact and influence this journal have – from citations to social media shares.
  • We’re committed to promoting your work as widely as we can and providing as much visibility and exposure for your article as possible.

Most Recent Articles

Asploro Journal of Biomedical and Clinical Case Reports [ASJBCCR] [ISSN: 2582-0370]
Original Article | Asp Biomed Clin Case Rep. 2022 Oct 22;5(3):146-51 | DOI: 10.36502/2022/ASJBCCR.6278
Seasonal Variation of Glucose Variability in Rather Elderly Patients with Type 2 Diabetes (T2D) Treated by Vildagliptin and Metformin (EquMet)

Author(s): Hiroshi BANDOiD*, Hisako YAMASHITA, Yoshinobu KATO, Takafumi KAWATA, Yoshikane KATO, Hiroe KANAGAWA


Background: Seasonal variation of HbA1c has been in focus.
Patients and Methods: The protocol included type 2 diabetes (T2D) patients (n=26, 71.4±10.2 years) on vildagliptin and metformin (EquMet) and HbA1c changes in 4 seasons for 6 years.
Results: HbA1c values ranged 6.9-7.5%, and tend to show highest in winter, and rather lower in autumn.
Discussion & Conclusion: Rather elderly T2D cases can tolerate EquMet with fair control. Previous reports showed a similar tendency. Some factors may be involved in the variation, such as temperature, climate, carbohydrate intake, Ramadan, and others. Furthermore, blood pressure and cardiovascular disease (CVD) can also influence them.

Asploro Journal of Biomedical and Clinical Case Reports [ASJBCCR] [ISSN: 2582-0370]
Case Report | Asp Biomed Clin Case Rep. 2022 Sept 24;5(3):140-45 | DOI: 10.36502/2022/ASJBCCR.6277
2022 Monkeypox Case Report: Beyond Borders and Expectations

Author(s): Satori IwamotoiD*, Leilani Hernandez, Harrison ChuiD, Hillary ChuiD, Mason Johnstone


Monkeypox is a zoonotic virus that is in the same family as smallpox. It is primarily spread through various forms of close contact with an infected individual, including direct contact with an infected person’s bodily fluids or surfaces and fabrics that have been contaminated. Its symptoms are generally characterized by rashes or lesions that are firm or supple, restricted to its area, and raised in its center. Vaccines for this disease were actually developed for smallpox. There are two main types of vaccinations: ACAM2000 and 0Jynneos. ACAM2000 uses a live vaccine virus while Jynneos uses a non-replicating virus. Due to the similarity between smallpox and monkeypox, Tpoxx is being researched as a potential treatment. FDA approved Tpoxx – or Tecovirimat – in 2018 as an effective treatment for smallpox after extensive animal trials and safety studies. Currently, the drug is not FDA-approved for monkeypox; however, under an expanded access protocol, it is clinically available. There are two cases presented in this article. The first case was a heterosexual male in his 30s who contracted monkeypox while having multiple sexual encounters with women while moving from tent to tent as an unhoused resident. He also shared pipes with others for recreational marijuana use. This case illustrates that monkeypox is a virus that isn’t restricted to sexuality, especially that of the LGBTQ+ community. To clarify, this virus is not an STI/STD, it’s spread by skin-to-skin contact, contact with an object that was in contact with an infected individual, or contact with respiratory secretions. However, there are fears of singling out the LGBTQ+ community and using the monkeypox virus to stigmatize these communities, much like the AIDS pandemic in the 1980s. In this case, a large proportion of those infected identifies as non-heterosexual, which may just be a result of the nature of a viral illness. Tightly knit groups and communities that spend a lot of time with each other create many opportunities for contact and facilitate disease spread. Second case is a homosexual male in his 60s who received childhood vaccination for smallpox, and yet contracted the monkeyvirus during his travels to Germany and Switzerland, where he had encountered multiple sex partners. This case presents how previous vaccination for smallpox may not be effective against monkeypox virus. Thus, prior smallpox vaccines in the distant past offered no protection against monkeypox and are capable of spreading to people outside of the borders of LGBTQ+ community.

Asploro Journal of Biomedical and Clinical Case Reports [ISSN: 2582-0370]
Original Article | Asp Biomed Clin Case Rep. 2022 Sept 12;5(3):128-39 | DOI: 10.36502/2022/ASJBCCR.6276
Analysis of the Work Environment and Burnout among Nurses, Technicians and Nursing Assistants in Brazilian Institutions

Author(s): Lucianna Reis Novaes*, Michel Matos de Barros, Fabrício dos Santos Cirino


In addition to causing damage to the health of patients, the Covid 19 pandemic has brought a greater burden to health systems directly affecting professionals, leading many to physical and emotional exhaustion. The present study aims to demonstrate the perceptions of the professional practice environment of nurses, technicians and nursing assistants through the use of the Environment of Professional Practice research (Practice Environment Scale of the Nursing Work Index – PES/NWI) and the Maslach Burnout Inventory (MBI), in addition to comparing them. The researches were applied in private and public administrative institutions in four Brazilian states, these being Amazonas (AM), Minas Gerais (MG), Mato Grosso do Sul (MS) and Rio de Janeiro (RJ) that are part of the IQG Nursing Certification, from December 2020 to June 2021, with the participation of 1484 professionals from the six invited institutions. The nursing team-physician relationships are identified as the most favorable characteristics of the work environment in the PES/NWI, and the foundations for nursing practice, however, identified as unfavorable to the participation of nursing in hospital affairs and adequacy of personnel and resources. Regarding the dimensions of the MBI research the best results are related to emotional exhaustion. However, the rates of low professional fulfillment were 69.1%. There are impacts on burnout related to emotional exhaustion and professional fulfillment related to the work environment, more frequently in the group of nurses. The analysis showed differences in the perceptions of nurses when compared to nursing assistants and technicians, with attention to inter-professional working relationships and the availability of resources. Therefore, the importance of guiding actions aimed at the management of these health resources is portrayed, with attention to the risk to the quality and safety of care, but also to the health of these professionals. The role of the leader, represented by the nurse, needs more attention and preparation, given its potential in guiding the best practices, professional engagement and promoting changes in the environment of professional practice.

Asploro Journal of Biomedical and Clinical Case Reports [ISSN: 2582-0370]
Case Report | Asp Biomed Clin Case Rep. 2022 Aug 19;5(3):113-19 | DOI: 10.36502/2022/ASJBCCR.6274
Investigation of Insulin Secretion in Glucose Tolerance Test by the Intake of Novel Imeglimin (Twymeeg)

Author(s): Hiroshi BANDO*, Hiroko OGAWA, Hirohisa URASAKI, Shinji NAGAHIRO, Hiroko URASAKI, Miwako NAKANISHI, Osami WATANABE


Background: Recent pharmacological studies reveal imeglimin (Twymeeg) including dual mechanisms for stimulating insulin secretion and reducing insulin resistance.
Case Presentation: The case is a 62-year-old male with type 2 diabetes (T2D). He showed HbA1c 6.4% and started imeglimin. After 5 weeks, a 75g oral glucose tolerance test (75gOGTT) was conducted, and the biomarkers were compared with that of 6 months ago. Insulinogenic index (IGI) 0-30min was stable, but insulin secretion was increased during 30-60min and 60-120min.
Discussion: Previous studies of imeglimin revealed improved insulin secretion for GTT. Clinical progress will be followed up with detailed investigation of glucose and insulin variability.

Asploro Journal of Biomedical and Clinical Case Reports [ISSN: 2582-0370]
Review Article | Asp Biomed Clin Case Rep. 2022 Aug 17;5(2):105-12 | DOI: 10.36502/2022/ASJBCCR.6273
A Review of Current Situation of Ultrasound Guided Nerve Block in Anesthesiologists’ Skill Training

Author(s): Xi Yang, Cong Chen*


In recent years, ultrasound-guided neuronal block had gradually become an indispensable skill for anesthesiologists in clinical work. Its visualization in operation makes the puncture more accuracy and anesthesia more effect, which effectively reduced the occurrence of related complications. However, it is not easy to master the ultrasound-guided neuronal block skill. Since the complexity of the knowledge system of ultrasound-guided nerve block, it makes the learning process cost more and learning period longer. So that the related teaching and training are facing great challenges. With the continuous innovation of teaching and training concepts and methods, a large number of teaching and training methods related to nerve block ultrasound-guided neuronal block had emerged, but there was still lacking a standardized, scientific and systematic teaching and training system in this field of medical education. Our review systematically summarized the current situation of ultrasound-guided nerve block training and reported the emergence of new forms and new methods in each link of teaching and training. We aimed to provide a sufficient and powerful reference for the reform and optimization of teaching system in this field.

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