Asploro Journal of Biomedical and Clinical Case Reports is an open access, peer-reviewed journal which mainly aims to directly improve global health outcomes and share clinical knowledge using case reports to convey important best practice messages. Each case report published in this journal adds valuable new information to medical knowledge.
Journal of Health Care and Research is an open access international journal publishing original peer-reviewed research articles. The Journal is a Tri-annually Publication. It is dedicated to the production of commitments in all fields of exploratory and connected inquires about health sciences. The editors welcome unique commitments that have not been published and are not under thought somewhere else.
Diabetes Research: Open Access is an Open Access Journal which releases Scholarly Articles featuring the content about Diabetes and Endocrinology.
The extent of the journal incorporates endocrine organs, hormonal discharges, hormonal receptors and the hormone controlled metabolic pathways. It also includes the clinical investigation of disorders related to Diabetes.
Asploro Journal of Pediatrics and Child Health is an international peer-reviewed open access journal in which it addresses not only health related issues but also aims to cover topics related to the physical, emotional and social well-being of children. Child psychology, behavioral aspects, societal apathy, exposure to the criminal and violent environment, parental negligence, and cultural background, are some of the factors that influence the development of a child; and any research related to these issues will be accepted for publication.
Most Recent Articles
Case Report | Asp Biomed Clin Case Rep. 2021 Apr 12;4(2):88-92 | DOI: 10.36502/2021/ASJBCCR.6235
Author(s): Xin Tian, Suling He, Runxiang Li* , Jianqin Wang*
Multiple adult xanthogranuloma (MAXG) is an uncommon adult form of xanthogranuloma. The clinical manifestation of MAXG is relatively rare, but it has characteristic histopathological and immunohistochemical features. MAXG is mainly associated with cutaneous damage, and extracutaneous manifestations such as cervical spine, intracardiac, and periocular lesions have rarely been reported. In patients with systemic association, clinicians should pay attention to the possibility of hematological malignancies. We report the case of a 17-year-old man with multiple lesions on the head, face, neck, arms and trunk, along with the clinical manifestations and pathological features.
Original Article | J Health Care and Research. 2021 Apr 26;2(1):63-69 | DOI: 10.36502/2021/hcr.6190
Why Orthopedic Surgery for Elderly Indicates that the Maryland Total Cost of Care Model should be Universally Adopted
Author(s): Bernard Pettingill, Jr.*
Arthritis has been described as the disease which kills the fewer spread cripples the most. With the aging of the population in the United States and the antiquated DRG reimbursement system for hospital surgical intervention, it is inevitable that the Medicare assistant will bankrupt itself prior to the proposed bankruptcy date of 2026 if changes are not made. It may change would be to insist that the system in Maryland for reimbursement to hospitals for essential joint replacement surgery of the elderly be adapted nationwide.
Original Article | J Health Care and Research. 2021 Apr 20;2(1):52-62 | DOI: 10.36502/2021/hcr.6189
Impact of Early Initiation of Continuous Renal Replacement Therapy in Critically Ill Patients with Acute Kidney Injury
Author(s): Jihyun Yang, Sung Yoon Lim, Shin Young Ahn, Gang-Ji Ko, Se Won Oh, Myung Gyu Kim, Won Yong Cho, Sang Kyung Jo*
Background: Although continuous renal replacement therapy (CRRT) has become the most commonly used modality for critically ill patients with acute kidney injury (AKI), the optimal timing of initiation remains controversial. CRRT is usually initiated when conventional indications of AKI arise; however, preemptive therapy may be beneficial. We evaluated the prevalence of preemptive and conventional CRRT initiation in critically ill patients and compared the associated 90-day mortality and renal recovery.
Methods: This retrospective study was performed in 2 tertiary centers between 2014 and 2017. Patients were divided into preemptive and conventional groups according to CRRT indications at the time of initiation. The primary clinical outcomes were 90-day mortality and renal recovery. Renal recovery was defined as a creatinine clearance of ≥15 mL/min and no need for renal replacement therapy for an additional 90 days.
Results: Patients with preemptive initiation showed higher diastolic blood pressure, higher bicarbonate level, lower blood urea nitrogen, and lower initial 6-h urine output at the time of initiation. More required simultaneous extracorporeal membrane oxygenation. This group showed a significantly lower 90-day mortality and higher renal recovery rate. In multivariate analysis, late initiation of CRRT remained an independent risk factor for increased 90-day mortality and lack of renal recovery in survivors.
Conclusion: Our study demonstrated that early preemptive CRRT initiation is associated with significantly lower 90-day mortality and higher renal recovery. Additional large-scale randomized controlled trials are needed to determine the optimal timing of therapy.
Original Article | J Health Care and Research. 2021 Apr 19;2(1):46-51 | DOI: 10.36502/2021/hcr.6188
Author(s): NDJE NDJE Mireille*
Adolescent problems constantly evolve due to societal and demographic factors and the changes taking place in adolescents. Supporting adolescents in schools is an enriching and fulfilling experience. This complex work allows us to see not only the wealth of skills, diverse perspectives, resilience and motivation adolescents display during their schooling process, but also the difficulties they encounter in the process. From 2008/2009 to 2017/2018 academic year (10 years), 2,916 students from form one to upper six in a college in Cameroon, with various requests was supported. Adolescents were supported by intruding into their psychic, school and family worlds, to understand the influence of the events that they experience on their learning. With the help of clinical interviews and educational talks, they were able to overcome several challenges facing them at home and in their social environment at school, a different social system in which they must navigate to find their feet. Adolescents can suffer from parental disaffection, anxiety, poor family interactions, adolescent crisis, and even socio-economic precariousness of parents, violence, loss, bereavement and sometimes mental imbalance. The main difficulties are due to family dysfunction. Psychoeducation, helping relationship, counselling and psychotherapy were the means by which the adolescents were helped to regain their self-confidence, and have a sense of security in school, to find their way despite the daily family dysfunctions.
Case Report | Asp Biomed Clin Case Rep. 2021 Apr 06;4(1):77-83 | DOI: 10.36502/2021/ASJBCCR.6233
Author(s): Hiroshi Bando*, Yoshinobu Kato, Yoshikane Kato, Sayuri Matsuzaki, Shinnichi Waka, Katsunori Ogura
The patient is a 56-year old (yo) female with type 2 diabetes mellitus (T2DM). Medical histories include persisting T2DM from 35yo, renal stone at 43yo, hypertension from 45yo, photocoagulation for retinopathy on 54yo. An incidentaloma was found in the left adrenal gland, where endocrinological exams were negative for functional tumor. Her diabetic control situation became worse with HbA1c > 10%, then the treatment has been changed from multiple daily injection (MDI), Dulaglutide to Xultophy which is combined agents of degludec and liraglutide (IDegLira). It was provided 10-18 doses daily, and then glucose variability profile was improved satisfactory, suggesting the dual synergistic effects.
Original Article | Asp J Pediatrics Child Health. 2021 Mar 02;3(1):18-29 | DOI: 10.36502/2021/asjpch.6164
Author(s): Marie Brunelli*, Li Niu, Christine Soghomonian, Anthony Salandy
his study aims to understand the association among sport participation, substance use and mental health of adolescent athletes within a diverse urban youth population. Data included a convenience sample of predominantly Black and Hispanic youth (85.7%) ages 14 to 18 years, who were Mount Sinai Adolescent Health Center (MSAHC) patients who presented for an annual physical exam or pre-participation exam (PPE) and were cleared for high school sport(s) participation. During the encounter, participants self-reported their use of tobacco, alcohol, and marijuana on a 6-point frequency scale, dichotomized to indicate use in the past 30 days. Anxiety and depression were assessed using two self-reported questions. Demographic data (e.g. ethnicity, gender, age) and whether participants had a current mental health provider were also extracted from the Electronic Medical Record (EMR). Results from multivariate logistic regression analyses showed adolescents with one year of sport participation had significantly lower odds of alcohol use in the past 30 days (OR=0.22, 95%CI= [0.12,0.41]) compared to individuals who did not participate in sport(s). Adolescents with two or more years of sport participation had significantly lower odds of alcohol (OR=0.46, 95%CI= [0.23,0.93]) and marijuana use (OR=0.10, 95%CI= [0.01,0.72]) in the past 30 days compared to individuals who did not participate in sport(s). Adolescents with one year of sport participation had lower odds of reported depression (OR=0.56, 95%CI= [0.33,0.94]) compared to individuals who did not participate in sport(s). Adolescents with two or more years of sport participation had significantly lower odds of reported depression (OR=0.35, 95%CI= [0.16,0.75]) and anxiety (OR=0.36, 95%CI= [0.15,0.86]) compared to individuals with no sport participation. These effects were found after adjusting for whether they were currently engaged with a mental health provider. Results of this study suggest that engagement in organized sport(s) may have protective effects against substance use, depression and anxiety. Additionally, the PPE could be used as an opportunity to promote engagement in extracurricular activities in addition to organized sports, to maximize the opportunity for adolescents to experience these benefits.
Review Article | Asp J Pediatrics Child Health. 2021 Mar 01;3(1):11-17 | DOI: 10.36502/2021/asjpch.6163
Author(s): Sarah Rotondo-Trivette, Sonia Michail*
Inflammatory bowel disease is an important pediatric disease, with as many as 25% of cases presenting during childhood. In this article, we review the types, etiology epidemiology, presentation, diagnosis, and management of pediatric inflammatory bowel disease. We also highlight the unique aspects of pediatric-onset inflammatory bowel disease versus adult-onset and future directions in this field, such as the use of genetic studies and ultrasound for the management of pediatric patients with inflammatory bowel disease.
Case Report | Asp Biomed Clin Case Rep. 2021 Mar 12;4(1):72-76 | DOI: 10.36502/2021/ASJBCCR.6232
Author(s): Foli Yvon Agbeko*, Mawouto Fiawoo, Rollin Arnaud Djomaleu, Magnoulelem NZonou, Sollim Talboussouma, Manani Hemou, Homba Daké Batalia, Rachel Bayahou Kérékou, Mazama Pakoudjare, Kokouvi Evenyo Abalo, Bayaki Saka, Deladem Koffi Azoumah, Edem Koffi Djadou, Kokou Nadiedjoa Douti, Komlatsè Gamedzi Akakpo-Numado, Adama Dodji Gbadoe, Yawo Dzayissé Atakouma
Introduction: CHD is a condition, which is frequent in pediatrics in the Caucasian population, remains rare in the Black population, and exceptional in sub-Saharan Africa.
The Patient: We report this first Togolese case of bilateral congenital dislocation of the hip associated with genu recurvatum observed in a newborn received on the second day of life.
The Primary Diagnoses, Interventions, and Outcomes: The pediatric examination had noted extension of lower limbs. The thighs were in adduction with a stiff bilateral genu recurvatum. The abduction of the thighs on the pelvis was considerably limited. The Barlow and Ortolani maneuvers showed a protrusion. There was also a camptodactyly of the thumbs and a cleft palate. The rest of the examination was normal. Ultrasound of the hip showed a bilateral congenital dislocation of the hip with an estimated acetabular fundus of 7 mm on both the right and left sides. Ultrasound and radiography of the knees were normal.
Conclusion: Clinical examination at birth is the key step in diagnosis of congenital hip dislocation. In situations where diagnosis is difficult, ultrasound is of capital importance. Treatment is in the majority of cases orthopedic.
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