ASPLORO OPEN ACCESS PUBLICATIONS
An international, peer-reviewed open access journal in which it addresses not only health related issues (disease, infection, genetic disorder, growth impairment etc.), but also aims to cover topics related to the physical, emotional and social well-being of children.
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor of the gastrointestinal tract and the stomach is the most affected site. Clinical manifestation is erratic depending on the tumor’s location, size, histological type, and stage. Ultrasound is useful in detecting gastric intramural tumor whereas computed tomography is the imaging modality of choice in further evaluating tumor characteristics and expansion, treatment planning, and monitoring recurrence. Definite diagnosis of GISTs is based on the immunohistochemical study. Early diagnosis and complete surgical resection of the tumor yield good long-term outcomes. We present a case of a small gastric GIST which was early detected and treated and the patient has tumor-free during 8 years of follow-up.
Palmar fibromatosis (Dupuytren contracture) is the nodule formed on the palmar face of the hand and the contracture of the palmar fascia. It is a clinical disease that causes loss of function resulting in retraction and contracture of the flexor tendons of the hand. Here we summarize a case with a Dupuytren contracture affecting the four extremities and its treatment.
Background: Cardiometabolic diseases like type 2 diabetes, metabolic syndrome, heart failure, and other cardiovascular complications are the leading cause of mortality and morbidity across the globe. These conditions are directly attributed to modifiable behaviors such as sedentary activity, poor diet, excessive consumption of alcohol, or smoking. Efforts aimed towards their prevention and management are, therefore, not only essential in the accomplishment of the healthy populations but also for eliminating the associated cost and health burdens. Dietary change is an important approach to the promotion of cardiometabolic health. Omega 3 (C20–22 ω 3) polyunsaturated fatty acids have pleiotropic effects on the functioning of cells, control inflammatory factors, and cellular events in vascular endothelial cells and cardiomyocytes. The hypolipemic, anti-arrhythmic, and anti-inflammatory properties of fatty acids offer cardioprotection. Government agencies and national heart associations recommend increased consumption of omega 3 polyunsaturated fatty acids (PUFA) supplements and fish to prevent cardiometabolic diseases.
Purpose of the Study: The purpose of this study is to investigate the role played by ω-3 and ω-6 polyunsaturated fatty acids in promoting cardiometabolic health.
Methods: The research study searched databases such as MEDLINE®, Embase, PsycINFO, CINAHL® and the Cochrane Library for relevant research studies evaluating the function/benefits of polyunsaturated fatty acids particularly ω-3 and ω-6 polyunsaturated fatty acids in promoting cardiometabolic functions published between 2011 and 2020. A total of 77 research studies were identified and used in the meta-analysis.
Results: Results from the meta-analysis indicated that polyunsaturated fatty acids lower the risk for cardiovascular disease by limiting inflammation of blood vessels, reducing thrombosis, increasing levels of high-density lipoproteins, reducing levels of low-density lipoproteins, and reducing risk factors associated with hypertension.
Conclusion: Given the benefits of polyunsaturated fatty acids lower the risk for cardiovascular diseases indicted in the meta-analysis. Therefore, human diets must contain the required amounts of PUFA due to the associated benefits.
Molluscum contagiosum (MC) presents by skin lesions secondary to a viral skin infection at the expense of epidermal keratinocytes having appearances with specific intracytoplasmic inclusions caused by the smallpox virus. It is a frequent pathology that affects the skin and mucous membranes. The diagnosis of CD is easy, but when clinical features lack atypical lesions, it can hinder the diagnosis of CD. It is then that there is a need for early and easy diagnosis of CD by the ticket of the dermoscopy which is a non-invasive diagnostic tool that allows visualizing the different dermoscopic aspects that we describe through the same observation.
Unfortunately, 35 million people worldwide suffer from drug use disorder while only one in seven people receive treatment. The health impacts combined with the socioeconomic burden of drug abuse are too numerous to count. It is well known that all organ systems are adversely affected by drug use including but not limited to the cardiovascular, respiratory, neurological, and renal. We will focus our attention on the effects of Methamphetamines on the cardiovascular system. Methamphetamines are known to be highly addictive stimulants with significant cardiovascular implications. We have gathered information from the literature available on methamphetamine-associated cardiomyopathy (MACM) and will discuss a case of a 58-year-old male, with no past medical history, who presented with dyspnea secondary to MACM.
An 88-year-old male presented for a routine transthoracic echocardiogram. Dilated coronary sinus was noted, raising the suspicion for persistent left superior venous cava (PLSVC). An agitated saline study from the left upper extremity demonstrated a flow through the coronary sinus into the right ventricle in a parasternal long-axis view. A venogram from the right internal jugular vein showed the PLSVC drained into a much dilated coronary sinus (CS) that connected to the right atrium. The right superior vena cava was absent. PLSVC along with absent right superior vena cava is rare and the inadvertent CS cannulation may result in vessel perforation.
Tuberous sclerosis complex (TSC) is a rare genetic disorder that affects about 1 in 5000 individuals worldwide. It does can affect many organs, leading to benign tumors presenting preferentially in the skin, brain, and kidneys. We report the case of a young man with cutaneous angiofibromes who is incidentally diagnosed with renal angiomyolipoma. Tuberous sclerosis complex is a rare disease with multi-organic disorders, some of which are severe and often asymptomatic`. The role of the doctor is to make a good clinical and paraclinical examination and a good follow-up of these patients in order to save and improve their quality of life.