ARTICLES IN PRESS | YEAR-2022 | VOLUME-3 | ISSUE-1

Total hip replacement is one of the most successful orthopaedic operation of recent time. The outcomes of THR may be influenced by several factors including patient demographics, surgical technique and implant features. One of the most important surgeon-controlled factors is component positioning. Surgical positioning of the acetabular cup and femoral prosthesis remains fundamental to obtaining accurate implant fit and prevent hip dislocation or impingement. Different categories of robotic assistance have been established during the previous years and all of the technologies target accuracy and reliability to reduce complications, and enhance clinical outcomes.

Music has beneficial power physically and psychologically. Among Integrative Medicine (IM), music therapy (MT) has been useful, and authors have continued research for IM, MT, and piano-playing. Most pianists do not consider the movement of their fingers, because the memorized process is transformed into automatic action. The function may involve the neural signals from the superior parietal lobule to the primary motor area and dorsal premotor cortex, which is called the sensory-motor transformations. The supplementary motor area (SMA) in the frontal lobe seems to be involved in the function of beat-based timing, expression, and activity of musical behavior.

Many community members believe the vaccine is not effective against COVID-19 and that local hospitals are full of vaccinated patients with severe COVID-19. Furthermore, they feel national figures do not reflect local numbers. We aimed to analyze the profile of COVID-19 patients in our local community hospital in Sacramento, California to see if indeed most COVID-19 hospitalized patients are vaccinated. This is a retrospective cross-sectional study of COVID-19 patients that were admitted to a community hospital on August 26, 2021, during the delta variant surge. We analyzed the profile of patients in the hospital who had a positive COVID-19 test by PCR. A total of 96 COVID-19 patients were studied of which 20 are vaccinated and 76 are unvaccinated. The average age of hospitalized vaccinated patients with COVID-19 is 69 while unvaccinated patients is 52.6. Additionally, 24 patients were on high flow oxygen with only 3 of them being fully vaccinated. There are 26 patients in the ICU with COVID-19 of which only 3 are fully vaccinated. 21 of these ICU patients are on mechanical ventilation with only 2 being fully vaccinated. Our data is consistent with national trends. While breakthrough infections are inevitable, analysis shows that the elderly population is most significantly impacted. However, breakthrough infections tend to also be less severe. Importantly, the unvaccinated population with COVID-19 disease and hospitalization tend to be of younger age. Altogether, this data from our local hospital highlights and emphasizes the need for our community to be fully vaccinated to prevent COVID-19 disease and hospitalizations.

Introduction: Thyroid benign (TBN) and malignant (TMN) nodules are a common thyroid lesion. The differentiation of TMN often remains a clinical challenge and further improvements of TMN diagnostic accuracy are warranted. The aim of present study was to evaluate possibilities of using differences in chemical elements (ChEs) contents in nodular tissue for diagnosis of thyroid malignancy.
Methods: Contents of ChEs such as aluminum (Al), boron (B), barium (Ba), calcium (Ca), chlorine (Cl), coper (Cu), iron (Fe), iodine (I), potassium (K), lithium (Li), magnesium (Mg), manganese (Mn), sodium (Na), phosphorus (P), sulfur (S), silicon (Si), strontium (Sr), vanadium (V), and zinc (Zn) were prospectively evaluated in “normal” thyroid (NT) of 105 individuals as well as in nodular tissue of thyroids with TBN (79 patients) and to TMN (41 patients). Measurements were performed using a combination of non-destructive and destructive methods: instrumental neutron activation analysis with high resolution spectrometry of short-lived radionuclides and inductively coupled plasma atomic emission spectrometry.
Results: It was observed that in TMN tissue the mean mass fraction of I was lower while the mean mass fractions of K, Mg, and P were higher than in both NT and TBN groups of samples. It was demonstrated that I content is nodular tissue is the most informative parameter for the diagnosis of thyroid malignancy. It was found that “Sensitivity”, “Specificity” and “Accuracy” of TMN identification using the I level in the needle biopsy of affected thyroid tissue was significantly higher than that using US examination and cytological test of fine needle aspiration biopsy.
Conclusions: It was concluded that determination of the I level in a needle biopsy of TNs using non-destructive instrumental analytical method is a fast, reliable, and very informative diagnostic tool that can be successfully used as an additional test of thyroid malignancy identification.