Journal of Health Care and Research

Journal of Health Care and Research [ISSN: 2582-8967]

Abel Ning Caballero^1iD, Mariuska Forteza Sáez^1iD*, Migdalia Pérez Trejo^1iD, Danay Corrales Otero^1iD
1Paediatric Oncology Department, National Institute of Oncology and Radiobiology, Cuba

Corresponding Author: Mariuska Forteza Sáez ^{ORCID iD}
Address: Paediatric Oncology Department, National Institute of Oncology and Radiobiology, Cuba.
Received date: 03 March 2023; Accepted date: 21 March 2023; Published date: 28 March 2023

Citation: Ning A, Forteza M, Perez M, Corrales D. Bilateral Renal Infiltration by Burkitt Lymphoma: Case Report. J Health Care and Research. 2023 Mar 28;4(1):25-29.

Copyright © 2023 Ning A, Forteza M, Perez M, Corrales D. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

Keywords: Non-Hodgkin Lymphomas, Burkitt Lymphoma, Primary Renal Lymphoma, Anti-CD20 Monoclonal Agent, Rituximab

Abstract

Non-Hodgkin lymphomas represent the third leading cause of cancer in the pediatric age group. Primary renal lymphoma is an uncommon presentation. We describe the diagnosis and treatment of a 6-year-old boy who presented with bilateral renal involvement, abdominal pain, vomiting, and weight loss. Initial investigations were consistent with presumed non-oliguric end-stage renal disease and anemia. Subsequent imaging demonstrated enlarged kidneys bilaterally. Histology revealed a Burkitt lymphoma that was highly responsive to chemotherapy, including the anti-CD20 monoclonal agent rituximab. Specific treatment was introduced with corticosteroids, vincristine, cyclophosphamide, and rituximab, resulting in the resolution of acute renal failure within 72 hours and complete response at the second induction with ANHL 1131 protocol.