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Therapeutic Hypothermia: Its Potential and Questionable Role in Traumatic Brain Injury | Abstract

➣ Letter to the Editor

➣ Asp Biomed Clin Case Rep. 2019 Oct 30;2(2):84-86

Tieng Kong RL1*

1University of British Columbia, 2329 West Mall, Vancouver BC V6T 1Z4, Canada

Corresponding Author: Rowena Li Tieng Kong

Address: University of British Columbia, 2329 West Mall, Vancouver BC V6T 1Z4, Canada; E-mail: rowena.kong@alumni.ubc.ca

Received date: 14 October 2019; Accepted date: 24 October 2019; Published date: 30 October 2019

From the acute management of cardiac arrest and stroke to traumatic brain injury, the implementation of hypothermia therapy since the past two decades has progressed from various guidelines committees’ consideration of minimal benefit to mixed favorable outcomes being obtained from numerous randomized controlled trials. As far as cases of traumatic brain injury are concerned, there were evidences of positive benefit in terms of mortality rates and neurological outcomes. According to a systematic analysis by Peterson et al. (2008), the relative risks (RR) of mortality (95% confidence interval) in comparison with control treatment groups were lower in subgroups of hypothermic procedures which utilized a cooling duration of over 48 hours (RR = 0.51), delivered at a temperature range of 33 degrees Celsius and above that was defined as milder than below 33 degrees Celsius (RR = 0.77), and when the patient was rewarmed passively (RR = 0.49).

Citation: Tieng Kong RL. Therapeutic Hypothermia: Its Potential and Questionable Role in Traumatic Brain Injury. Asp Biomed Clin Case Rep. 2019 Oct 30;2(2):84-86.

Copyright © 2019 Tieng Kong RL. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

Keywords: Therapeutic Hypothermia; Temperature; Cooling; Intracranial Hypertension; Traumatic Brain Injury

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