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Self-controlled Case Series Study (SCCSS): A Novel Research Method | Abstract

El-Gilany AH1*

1Professor of Public Health & Preventive Medicine, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt

Corresponding Author: Prof. Abdel-Hady El-Gilany

Address: Professor of Public Health & Preventive Medicine, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt

Received date: 20 May 2019; Accepted date: 02 June 2019; Published date: 08 June 2019

Abstract

Self-controlled case series study (SCCSS) is a novel strategy to control between-person confounders by comparing the risk and reference periods in each patient. SCCSS investigates the association between transient exposure and an adverse event. It was developed to study adverse reactions to vaccines. Risk periods are defined during or after the exposure. Then the method finds a relative incidence i.e. the incidence in risk periods relative to the incidence in control periods. This editorial describes the definition, origins, design, assumptions, advantages, and limitations of this research method.

Citation: El-Gilany AH, “Self-controlled case series study (SCCSS): a novel research method”. Asp Biomed Clin Case Rep, vol.2, no.1: 29-32, 2019.

Copyright © 2019 El-Gilany AH, This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Key Words: Self-Controlled Case Series (SCCS); Consecutive Controlled Case Series (CCCS)

Abbreviation: Consecutive Controlled Case Series Study (CCCSS); Self-Controlled Case Series Method (SCCSM) and sometimes called case series study for simplicity.

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