Asploro Journal of Biomedical and Clinical Case Reports

Asploro Journal of Biomedical and Clinical Case Reports

Hiroshi Bando^1,2,3iD*
1Medical Research/Tokushima University, Tokushima, Japan
²Integrative Medicine Japan (IMJ), Shikoku Division, Tokushima, Japan
³Japan low carbohydrate diet promotion association (JLCDPA), Kyoto, Japan

Corresponding Author: Hiroshi Bando ^{ORCID iD}
Address: Tokushima University /Medical Research, Nakashowa 1-61, Tokushima 770-0943, Japan.
Received date: 25 February 2024; Accepted date: 29 March 2024; Published date: 06 April 2024

Citation: Bando H. Latest Trend and Perspective of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) as a Novel Nomenclature. Asp Biomed Clin Case Rep. 2024 Apr 06;7(2):84-87.

Copyright © 2024 Bando H. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

Keywords: Metabolic Dysfunction-Associated Steatotic Liver Disease, Nonalcoholic Fatty Liver Disease, National Health and Nutrition Examination Survey, Metabolic Dysfunction-Associated Fatty Liver Disease, Fatty Liver Index

Abbreviations: MASLD: Metabolic Dysfunction-Associated Steatotic Liver Disease; NAFLD: Nonalcoholic Fatty Liver Disease; NHANES III: National Health and Nutrition Examination Survey; MAFLD: Metabolic Dysfunction-Associated Fatty Liver Disease; FLI: Fatty Liver Index

Abstract

Recently, the medical term for nonalcoholic fatty liver disease (NAFLD) has been changed to a novel nomenclature: metabolic dysfunction-associated steatotic liver disease (MASLD). The latest report shows analyses of the National Health and Nutrition Examination Survey (NHANES III) using the fibrosis-4 index (FIB-4) and enhanced liver fibrosis (ELF). Among 6429 NAFLD cases, 99% met MASLD criteria. In another study with 4286 cases, 99% of steatosis cases met the MASLD definition, and 95.4% met the metabolic dysfunction-associated fatty liver disease (MAFLD) definition. Several biomarkers show a relationship with MASLD/MAFLD, such as BMI, T2D, HOMA-IR, central obesity, waist circumference, and CKD.