Asploro Journal of Biomedical and Clinical Case Reports

Asploro Journal of Biomedical and Clinical Case Reports

Jia-Li Jiang¹, Xue-Fei Li^1iD, Hai Yu^1iD*
1Department of Anesthesiology, West China Hospital, West China School of Medicine, Sichuan University, Chengdu, China

Corresponding Author: Hai Yu ^{ORCID iD}
Address: Department of Anesthesiology, West China Hospital, Sichuan University, 37 Guoxue Road, Chengdu 610041, Sichuan, China.
Received date: 24 July 2024; Accepted date: 10 August 2024; Published date: 17 August 2024

Citation: Jiang JL, Li XF, Yu H. Driving Pressure-guided Ventilation in the Intensive Care Unit and Operating Room. Asp Biomed Clin Case Rep. 2024 Aug 17;7(3):216-25.

Copyright © 2024 Jiang JL, Li XF, Yu H. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

Keywords: Mechanical Ventilation, Driving Pressure, Mortality, Postoperative Pulmonary Complications

Abstract

Mechanical ventilation is the cornerstone of management for critically ill patients and those undergoing general anesthesia. Currently, lung protective ventilation strategies primarily include low tidal volume, positive end-expiratory pressure, and limited pressure, combined with certain recruitment maneuvers. Recently, driving pressure has been proposed as a key parameter to optimize mechanical ventilation. This study reviewed the relevant literature and suggests that driving pressure may be correlated with improved survival in patients with acute respiratory distress syndrome, enhanced intraoperative pulmonary mechanics, reduced postoperative atelectasis, and better gas exchange and oxygenation, even in normal lungs. However, the correlation between driving pressure and postoperative pulmonary complications has also been described as controversial. These findings could serve as a reference for future clinical practice.