Stroke Secondary to Fibromuscular Dysplasia | Abstract

Asploro Journal of Biomedical and Clinical Case Reports

Asploro Journal of Biomedical and Clinical Case Reports

ISSN: 2582-0370

Article Type: Case Report

DOI: 10.36502/2023/ASJBCCR.6306

Asp Biomed Clin Case Rep. 2023 Jun 26;6(2):138-45

Ashwin Sidhu1ID*, Harrison Chu1ID
1California Northstate University, College of Medicine, Elk Grove, USA

Corresponding Author: Ashwin Sidhu ORCID iD and Harrison Chu ORCID iD
Address: California Northstate University, College of Medicine, Elk Grove, 9700 W Taron Drive, CA 95757, USA.
Received date: 06 June 2023; Accepted date: 20 June 2023; Published date: 26 June 2023

Citation: Sidhu A, Chu H. Stroke Secondary to Fibromuscular Dysplasi. Asp Biomed Clin Case Rep. 2023 Jun 26;6(2):138-45.

Copyright © 2023 Sidhu A, Chu H. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

Keywords: Fibromuscular Dysplasia, Left Ventricular Thrombosis, Stroke, Renal Disease, Case Report


FMD is a rare systemic vascular disease characterized by abnormal cell proliferation in the artery walls, leading to artery narrowing, twisting, or bulging. It commonly affects the carotid and renal arteries and can result in renal diseases and stroke. This paper presents a case study of a 39-year-old unhoused female patient who experienced a stroke secondary to fibromuscular dysplasia (FMD) and left ventricular thrombus. The patient presented with asymmetric movement of the extremities and psychosis, so intoxication was initially suspected. However, further examination revealed facial asymmetry and motor weakness. CT scans showed a left anterior cerebral artery infarction and irregular contour of the cervical internal carotid arteries, consistent with FMD and carotid thrombus. Management involved stabilizing the patient, providing supportive treatment, and controlling blood pressure. Thrombolytic therapy was not administered due to the time elapsed since symptom onset. The patient was started on anticoagulation for the carotid plaque and left ventricular thrombus. A transthoracic echocardiogram revealed a large left ventricular thrombus and left atrial enlargement, and the patient was started on heart failure medications.

FMD and left ventricular thrombus are not directly related, but FMD can contribute to thrombus development through its impact on the cardiovascular system, including hypertension, arterial wall damage, aneurysm development, or dissection. Treatment for FMD may involve medication, observation, or surgical interventions like angioplasty and stenting. Anticoagulation therapy is essential for managing the left ventricular thrombus.

This case highlights the importance of early diagnosis and treatment of FMD to prevent complications such as stroke. It is important to consider FMD in the diagnosis of younger patients with a stroke, especially those with a history of hypertension, substance abuse, or other risk factors. Further research is needed to better understand the relationship between FMD and stroke and to optimize treatment strategies for these patients.



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