Asploro Journal of Biomedical and Clinical Case Reports
Article Type: Commentary
Asp Biomed Clin Case Rep. 2021 Jun 30;4(2):110-13
1Medical Research/Tokushima University, Tokushima, Japan
2Integrative Medicine Japan (IMJ), Shikoku Island Division, Tokushima, Japan
Corresponding Author: Hiroshi BANDO, MD, PhD, FACP ORCID iD
Address: Tokushima University /Medical Research, Nakashowa 1-61, Tokushima 770-0943, Japan.
Received date: 25 May 2021; Accepted date: 23 June 2021; Published date: 30 June 2021
Citation: Bando H. Some Measures for COVID-19 Including Deep Ultraviolet Light-Emitting Diode (DUV-LED), Gc protein-derived Macrophage-Activating Factor (Gcmaf), and 5-Aminolevulinic Acid (5-ALA). Asp Biomed Clin Case Rep. 2021 Jun 30;4(2):110-13.
Copyright © 2021 Bando H. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.
Keywords: Light Emitting Diode, Deep Ultraviolet Light Emitting Diode, Gc protein-derived Macrophage-Activating Factor, 5-Aminolevulinic Acid, Protoporphyrin IX, Severe Acute Respiratory Syndrome Coronavirus-2
Abbreviations: LED: Light Emitting Diode; DUV-LED: Deep Ultraviolet Light Emitting Diode; Gcmaf: Gc protein-derived Macrophage-Activating Factor; 5-ALA: 5-Aminolevulinic Acid; PPIX: Protoporphyrin IX; SARS-Cov-2: Severe Acute Respiratory Syndrome Coronavirus-2
Several trials for the COVID-19 pandemic are found. Prof. Shunji Nakamura, Tokushima University was awarded the 2014 Nobel prize in Physics for light-emitting diodes (LEDs). Deep ultraviolet LED (DUV-LED) causes SARS-CoV-2 inactivation as 99.9% by 265 nm. Gc protein-derived macrophage-activating factor (GcMAF)-based immunotherapy has a wider application for serious infection, chronic fatigue syndrome, and cancers. Covid center in Naples submitted a phase II report concerning GcMAF and COVID-19 in Feb 2021. 5-aminolevulinic acid (5-ALA) and its metabolite protoporphyrin IX (PpIX) show anti-inflammatory and antiviral effects for Zika, Dengue, influenza A viruses, and SARS-CoV-2. These results hopefully contribute to the research development for COVID-19.