Asploro Journal of Biomedical and Clinical Case Reports

Asploro Journal of Biomedical and Clinical Case Reports

Abel Ning Caballero^1iD*, Kandecy Archer-Austin^1iD
1Oncology Department, Georgetown Public Hospital Corporation, Guyana

Corresponding Author: Abel Ning Caballero ^{ORCID iD}
Address: Guyana Public Hospital Corporation, Georgetown, Guyana.
Received date: 17 July 2024; Accepted date: 12 August 2024; Published date: 19 August 2024

Citation: Caballero AN, Archer-Austin K. Hepatoblastoma: A Case Report. Asp Biomed Clin Case Rep. 2024 Aug 19;7(3):226-32.

Copyright © 2024 Caballero AN, Archer-Austin K. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

Keywords: Hepatoblastoma, Liver Tumor, Hepatectomy

Abstract

Hepatoblastoma is a rare type of pediatric malignant disease and represents the most frequent cause of liver tumors during childhood. We describe the diagnosis and treatment of a 14-month-old female patient who presented with abdominal swelling, anorexia, and weight loss. Initial investigations indicated elevated alpha-fetoprotein levels and thrombocytosis. A CT scan showed a heterogeneous mass arising in the right lobe of the liver. Histology revealed hepatoblastoma, epithelial type, and fetal pattern. The patient was treated as a standard risk according to the Pretext classification (Pretext I-III) with neoadjuvant Cisplatin (4 cycles) following the SIOPEL 3 protocol, resulting in a 40% reduction in tumor size and a successful partial hepatectomy.