Diabetic Elderly with Keeping Less Arteriosclerosis Treated by Imeglimin (Twymeeg) | Abstract

contact@asploro.com

Diabetic Elderly with Keeping Less Arteriosclerosis Treated by Imeglimin (Twymeeg) | Abstract

Asploro Journal of Biomedical and Clinical Case Reports

ISSN: 2582-0370

Article Type: Case Report

DOI: 10.36502/2024/ASJBCCR.6348

Asp Biomed Clin Case Rep. 2024 May 28;7(2):126-30

Full Text HTML

Full Text PDF

Hiroshi Bando^1,2,3iD*, Maki Okada³, Noboru Iwatsuki³, Tomoya Ogawa³, Kazuki Sakamoto³
¹Medical Research/Tokushima University, Tokushima, Japan
²Japan Low Carbohydrate Diet Promotion Association, Kyoto, Japan
³Sakamoto Hospital, Higashi Kagawa city, Kagawa, Japan

Corresponding Author: Hiroshi Bando ^{ORCID iD}
Address: Tokushima University /Medical Research, Nakashowa 1-61, Tokushima 770-0943, Japan.
Received date: 04 May 2024; Accepted date: 20 May 2024; Published date: 28 May 2024

Citation: Bando H, Okada M, Iwatsuki N, Ogawa T, Sakamoto K. Diabetic Elderly with Keeping Less Arteriosclerosis Treated by Imeglimin (Twymeeg). Asp Biomed Clin Case Rep. 2024 May 28;7(2):126-30.

Copyright © 2024 Bando H, Okada M, Iwatsuki N, Ogawa T, Sakamoto K. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

Keywords: Imeglimin, Twymeeg, Pulse Wave Velocity, Ankle Brachial Index, Cardio-Ankle Vascular Index, Japan LCD Promotion Association

Abbreviations: PWV: Pulse Wave Velocityl ABI: Ankle Brachial Index; CAVI: Cardio-Ankle Vascular Index; JLCDPA: Japan LCD Promotion Association

Abstract

The patient is a 73-year-old male with type 2 diabetes (T2D) and hypertension, treated for years with various oral hypoglycemic agents (OHAs) and an anti-hypertensive agent (AHA). His HbA1c levels were unstable during 2020-2022, during which time he was prescribed linagliptin, voglibose, and metformin. In 2023, his HbA1c increased to 8.4%, and imeglimin (Twymeeg) was initiated. This resulted in an acute reduction of HbA1c to 6.5% over 5 months. A pulse wave velocity (PWV) examination, using a sphygmograph, showed stable values for the cardio-ankle vascular index (CAVI) and ankle-brachial index (ABI) over 4 years. Consequently, this patient has maintained a low level of arteriosclerosis, associated with the effective treatment using imeglimin.