1Consultant, Department Of Dermatology, Universitas Academic Hospital, Bloemfontein, South Africa
Corresponding Author: Frans Maruma, MBChB, Dip-Hiv-Med, MMed, AAAM, FC Derm
Address: Department of Dermatology, University Of Free State, Faculty Of Health Sciences, Bloemfontein, South Africa.
Received date: 03 September 2020; Accepted date: 21 September 2020; Published date: 30 September 2020
Citation: Maruma F. Pulse Treatment Using Azithromycin in HIV/AIDS-Associated Solitary Tumor-Like Bacillary Angiomatosis. Asp Biomed Clin Case Rep. 2020 Sept 30;3(3):217-20.
Copyright © 2020 Maruma F. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.
Keywords: Warthin Starry Stain, Azithromycin, Pulse Therapy, Immunocompromised, HIV/AIDS
Abbreviations: PCR - Polymerase Chain Reaction, HIV/AIDS - Human Immune Deficiency Virus/Acquired Immuno Deficiency Syndrome
With the advent of the HIV/AIDS pandemic within the South Saharan region, clinicians are faced with accentuated clinical presentations of previously well-known diseases. Bacillary angiomatosis is no exception to this rule. Bacillary angiomatosis is a cutaneous and systemic bacterial infection caused by gram-negative Bartonella species. We report a case of an immunocompromised 44 years old female patient who presented with a solitary tumor-like bacillary angiomatosis that was treated successfully with azithromycin in a bi-weekly pulsed dosing regimen. This patient had a considerably large (12 x 10cm’s) single lesion of the disease. The case highlights the potential that immunosuppressed patients are not only at risk of disseminated disease, but also of developing severe localized disease. Furthermore, Azithromycin pulse treatment may offer a convenient alternative as there is still no clear consensus regarding treatment protocol for using azithromycin in the treatment of cutaneous bartonellosis.