Asploro Journal of Biomedical and Clinical Case Reports

Asploro Journal of Biomedical and Clinical Case Reports

Naoki Kondo¹, Hiroshi Bando^1,2,3iD*, Masaki Okada¹, Noboru Iwatsuki¹, Tomoya Ogawa¹, Kazuki Sakamoto^1
1Sakamoto Hospital, Higashi Kagawa city, Kagawa, Japan
²Medical Research/Tokushima University, Tokushima, Japan
³Japan Low Carbohydrate Diet Promotion Association (JLCDPA), Kyoto, Japan

Corresponding Author: Hiroshi BANDO, MD, PhD, FACP ^{ORCID iD}
Address: Tokushima University /Medical Research, Nakashowa 1-61, Tokushima 770-0943, Japan.
Received date: 20 August 2023; Accepted date: 02 September 2023; Published date: 09 September 2023

Citation: Kondo N, Bando H, Okada M, Iwatsuki N, Ogawa T, Sakamoto K. Type 2 Diabetes (T2D) Case with Digestive and Cardiovascular Disorders Treated by EquMet and Twymeeg. Asp Biomed Clin Case Rep. 2023 Sept 9;6(3):233-40.

Copyright © 2023 Kondo N, Bando H, Okada M, Iwatsuki N, Ogawa T, Sakamoto K. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

Keywords: Diabetic Gastroenteropathy, Magnesium Oxide/Picosulfate, Twymeeg, Plethysmography, Cardio-Ankle Vascular Index

Abbreviations: CAVI: Cardio-Ankle Vascular Index

Abstract

This case involves a 76-year-old female patient with type 2 diabetes (T2D), diabetic gastroenteropathy, and slight arteriosclerosis. Her HbA1c levels have been unstable for years due to her typical carbohydrate intake. Her symptoms include constipation, nausea, and abdominal fullness. Despite being on magnesium oxide and picosulfate, she experiences difficulty achieving smooth bowel movements for an extended period.
In March 2023, her HbA1c levels increased to 8.5%. Subsequently, EquMet and Twymeeg were initiated, resulting in remarkable clinical effects, with her HbA1c dropping to 5.9% by August 2023. A Holter ECG recorded ventricular premature contractions (VPC) occurring 10 times (0.010%) over a 24-hour period. Additionally, plethysmography indicated a cardio-ankle vascular index (CAVI) of 9.5/9.3, suggesting slight arteriosclerosis.