VOLUME-3 | ISSUE-2 | YEAR-2021 [May to August]
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Original Article | Open Access | Asp J Pediatrics Child Health. 2021 Jul 06;3(2):40-47
Short Term Survival of Extreme Preterm Newborns at 23–26 Weeks’ Gestation in a Middle East Modern Referral Maternity Hospital
Ashraf Mansour, Husam Salama*, Sufwan Alomar, Sabry Ahmed, Nazla Mahmoud, Ratheesh Paramban, Mohamed Mahma
Pages: 40-47 | First Published: 06 July 2021 | DOI: 10.36502/2021/asjpch.6167
Caring about ELBW newborns at the limit of viability is demanding with a high rate of mortality and long-term morbidity. Society expectations become high and persistent while health care coast inside NICU is very high.
Case Report | Open Access | Asp J Pediatrics Child Health. 2021 Aug 12;3(2):48-51
A Preventable Cause of Hypotonia in Infants: Case Report of Two Infants with Vitamin B12 Deficiency
Akhrif M*, Saghir S, Kmari M, Ourrai A, Hassani A, Abilkassem R, Agadr A
Pages: 48-51 | First Published: 12 August 2021 | DOI: 10.36502/2021/asjpch.6168
Innate deficits in the metabolism or transport of vitamin B12 are exceptional. The main cause of vitamin B12 deficiency in infants is secondary to maternal deficiency. Maternal deficiency can have a vegan diet, low socio-economic level (developing countries) and a high level of development with a poor diet) or digestive pathologies responsible for a lack of absorption. The clinical signs are not very specific (developmental delay, pallor, hypotonia, vomiting and diarrhoea), which explains the frequent delay in diagnosis. The pathophysiology of the neurological damage, which is still uncertain, is thought to be secondary to a defect in myelination with altered nerve conduction and cortical atrophy. The aim of this work is to underline the importance of raising awareness of vitamin B12 deficiency in order to avoid its profound neurological repercussions, especially as substitution treatment allows an improvement or a reversibility of the neurological damage and raises the question of the possibility of screening new-borns.