The vulvar region is a complex area because it comprises many elements, besides the skin itself. Therefore, it can present a variety of relatively rare tumors that can be classified based on source tissue (epithelial or mesenchymal). Benign epithelial tumors in the connective tissue are not often diagnosed in the vulvar area, which is mostly affected by fibroepithelial polyps.
Fibroepithelial polyps mainly affect obese and diabetic women. However, assumingly, hormonal disorders can enable the development of such tumors, which have no association with human papillomavirus and preferably affect skinfold areas such as armpits and neck. In macroscopic terms, fibroepithelial polyps can appear as a grayish lesion, as a condyloma-like pigmented papillomatous growth, or as a pedicular and hypopigmented tumor. They are often asymptomatic and diagnosed by patients themselves. Their clinical manifestations are associated with skin rashes or ulcers (the large ones) in obese women. Other benign tumors, such as leiomyomas, can also affect the vulvar region. In addition, there are reports of granulosa cell tumors that originated from peripheral nerves affecting this region.