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Satisfactory Rapid Response to Xultophy Associated with Meal Tolerance Test (MTT) by Carbohydrate Loading
Hiroshi Bando1,2,3*, Noboru Iwatsuki3, Kazuki Sakamoto3, Tomoya Ogawa3
1Tokushima University / Medical Research, Tokushima, Japan
2Japan Low Carbohydrate Diet Promotion Association, Kyoto, Japan
3Sakamoto Hospital, Higashi Kagawa City, Kagawa, Japan
Corresponding Author: Hiroshi BANDO, MD, PhD, FACP ORCID iD
Address: Tokushima University /Medical Research, Nakashowa 1-61, Tokushima 770-0943, Japan.
Received date: 06 July 2021; Accepted date: 05 August 2021; Published date: 12 August 2021
Citation: Bando H, Iwatsuki N, Sakamoto K, Ogawa T. Satisfactory Rapid Response to Xultophy Associated with Meal Tolerance Test (MTT) by Carbohydrate Loading. Asp Biomed Clin Case Rep. 2021 Aug 12;4(2):145-52.
Copyright © 2021 Bando H, Iwatsuki N, Sakamoto K, Ogawa T. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.
Keywords: Xultophy, Insulin Degludec and Liraglutide, Type 2 Diabetes Mellitus, Meal Tolerance Test, Postprandial Hyperglycemia
Abbreviations: IDegLira: Xultophy; T2DM: Type 2 Diabetes Mellitus; MTT: Meal Tolerance Test
The case is a 69-year-old male patient with Type 2 Diabetes Mellitus (T2DM) for 21 years. His diabetic control was not so satisfactory, and his HbA1c value increased in spring 2021. Then, he started Xultophy (IDegLira), which includes a fixed ratio of two agents of basal degludec and liraglutide. Just after providing Xultophy, the daily profile of blood glucose decreased from 179-400 mg/dL to 112-171 mg/dL, with remarkable clinical efficacy. He usually takes 80g of carbohydrates in breakfast, and the meal tolerance test (MTT) was challenged. As carbohydrate loading was given 100-75-50-0%, postprandial hyperglycemia at 60-min showed 277-219-159-133 mg/dL, respectively.