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Research Progress on the Correlation Between Delirium and Dementia
Yu Cai1*
1Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China
Corresponding Author: Yu Cai
Address: Department of Anesthesiology, West China Hospital, Sichuan University, No. 37, Guoxue Valley, Wuhou District, Chengdu, Sichuan 610041, China.
Received date: 30 December 2025; Accepted date: 08 January 2026; Published date: 16 January 2026
Citation: Cai Y. Research Progress on the Correlation Between Delirium and Dementia. Asp Biomed Clin Case Rep. 2026 Jan 16;9(1):07-13.
Copyright © 2026 Cai Y. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.
Keywords: Delirium, Dementia, Cognitive Dysfunction
Abstract
Delirium is an acute confusional state characterized by inattention, altered level of consciousness, and cognitive dysfunction, whereas dementia is an insidious, chronic, and progressive loss of previously acquired cognitive abilities. The occurrence of delirium is an independent risk factor for subsequent dementia, and conversely, patients with dementia have a significantly higher risk of developing delirium compared to the general population. Although the close relationship between the two is recognized, the specific mechanisms underlying their interaction remain unclear. In daily life and clinical practice, timely assessment of cognitive function and effective intervention in individuals experiencing delirium may potentially slow cognitive decline and even prevent the onset or progression of dementia. This article reviews the research on the correlation between delirium and dementia, exploring ways to mitigate or even reverse further cognitive deterioration in delirious patients.