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An Arteriosclerotic Diabetic Male with Clinical Effect by Low Carbohydrate Diet (LCD) and Vildagliptin/Metformin (EquMet)
Noboru Iwatsuki1, Hiroshi Bando1,2iD*, Maki Okada1, Tomoya Ogawa1, Kazuki Sakamoto1
1Sakamoto Hospital, Higashi Kagawa city, Kagawa, Japan
2Medical Research/Tokushima University, Tokushima, Japan
Corresponding Author: Hiroshi Bando ORCID iD
Address: Tokushima University /Medical Research, Nakashowa 1-61, Tokushima 770-0943, Japan.
Received date: 20 March 2026; Accepted date: 25 April 2026; Published date: 02 May 2026
Citation: Iwatsuki N, Bando H, Okada M, Ogawa T, Sakamoto K. An Arteriosclerotic Diabetic Male with Clinical Effect by Low Carbohydrate Diet (LCD) and Vildagliptin/Metformin (EquMet). Asp Biomed Clin Case Rep. 2026 May 02;9(2):50-54.
Copyright © 2026 Iwatsuki N, Bando H, Okada M, Ogawa T, Sakamoto K. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.
Keywords: Arteriosclerosis, Type 2 Diabetes, Pulse Wave Velocity, Cardio-Ankle Vascular Index, Ankle-Brachial Index
Abbreviations: T2D: Type 2 Diabetes; PWV: Pulse Wave Velocity; CAVI: Cardio-Ankle Vascular Index; ABI: Ankle-Brachial Index
Abstract
The case was a 75-year-old male with hypertension, dyslipidemia, type 2 diabetes (T2D), mild cognitive impairment (MCI), and a general presence of arteriosclerosis for years. HbA1c remained stable at about 7.1–7.4%, and otherwise, no remarkable biochemical results were observed. Pulse wave velocity (PWV) showed an ankle-brachial index (ABI) of 0.96/1.12 and a cardio-ankle vascular index (CAVI) of 9.1/8.6 (right/left), respectively. CAVI values remained stable for 6 years.
These results suggested the presence of generalized arteriosclerosis due to his previous diseases. He has been treated with vildagliptin/metformin (EquMet). From summer 2025, he maintained a low-carbohydrate diet (LCD) satisfactorily, and then HbA1c decreased to 6.0% in 2026.