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Actual Meal of Low Carbohydrate Diet (LCD) for Diabetic Patient Treated by Effective Imeglimin (Twymeeg)

Tomoko Kusumoto¹, Hiroshi Bando^1,2,3ID*, Kenji Hayashi¹, Eri Yasuoka¹, Michiaki Shibata¹, Hikaru Takagishi^1
1Hayashi Hospital, Tokushima, Japan
²Tokushima University/Medical research, Tokushima, Japan
³Japan Low Carbohydrate Diet Promotion Association (JLCDPA), Kyoto, Japan

Corresponding Author: Hiroshi BANDO, MD, PhD, FACP ^{ORCID iD}
Address: Tokushima University /Medical Research, Nakashowa 1-61, Tokushima 770-0943, Japan.
Received date: 12 July 2023; Accepted date: 24 July 2023; Published date: 31 July 2023

Citation: Kusumoto T, Bando H, Hayashi K, Yasuoka E, Shibata M, Takagishi H. Actual Meal of Low Carbohydrate Diet (LCD) for Diabetic Patient Treated by Effective Imeglimin (Twymeeg). Asp Biomed Clin Case Rep. 2023 Jul 31;6(3):178-85.

Copyright © 2023 Kusumoto T, Bando H, Hayashi K, Yasuoka E, Shibata M, Takagishi H. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.

Keywords: Low Back Pain, Lumbar Spinal Stenosis, Low Carbohydrate Diet, Imeglimin (Twymeeg), Trials of IMeglimin for Efficacy and Safety

Abbreviations: LBP: Low Back Pain; LSS: Lumbar Spinal Stenosis; LCD: Low Carbohydrate Diet; TIMES: Trials of IMeglimin for Efficacy and Safety

Abstract

The case is a 51-year-old male with obesity, type 2 diabetes (T2D), dyslipidemia, and hypertension. His HbA1c value increased to 8.0%, accompanied by oral semaglutide administration. Glucose variability was exacerbated after that, and then novel imeglimin (Twymeeg) was initiated. HbA1c decreased from 7.4% to 6.7% over 4 months with a 3 kg weight reduction. The case also had low back pain (LBP) and lumbar spinal stenosis (LSS), probably resulting from Metabolic syndrome (Met-S), and had actual experience with a low carbohydrate diet (LCD) in the hospital meals. Four patterns of LCD meals had carbohydrates ranging from 17.8g to 28.0g, with 501-690kcal.