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A Comprehensive Analysis of Influencing Factors and Clinical Insights into Perioperative Sleep Disorders
Rui Mao1, Hong Chang2*
1Department of Anesthesiology, Shangjin Nanfu Hospital, Chengdu, China
2Department of Anesthesiology, West China Hospital, Sichuan University, China
Corresponding Author: Chang Hong
Address: Department of Anesthesiology, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Wuhou District, Chengdu, Sichuan Province 610041, China.
Received date: 17 March 2025; Accepted date: 25 March 2026; Published date: 01 April 2026
Citation: Mao R, Chang H. A Comprehensive Analysis of Influencing Factors and Clinical Insights into Perioperative Sleep Disorders. Asp Biomed Clin Case Rep. 2026 Apr 01;9(1):27-33.
Copyright © 2026 Mao R, Chang H. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.
Keywords: Perioperative Period, Sleep Disorders, Risk Factors, Anesthesia, Circadian Rhythm, Postoperative Recovery
Abstract
Perioperative sleep disorders (PSDs), affecting approximately 60% of surgical patients, are a significant yet often overlooked challenge that hinders recovery and increases the risk of complications. This paper provides a systematic analysis of the complex mechanisms and key risk factors contributing to PSDs from four distinct dimensions. It identifies preoperative vulnerabilities such as baseline insomnia, obstructive sleep apnea (OSA), anxiety, and chronic comorbidities as primary predisposing factors. Furthermore, it examines the direct impacts of intraoperative factors, including the suppression of sleep architecture by anesthetic drugs (propofol, opioids) and the disruption of circadian rhythms caused by surgical timing and trauma. The review also highlights the synergistic exacerbation of sleep disturbances in the postoperative phase due to pain–inflammation cycles, adverse ward environments (noise and light), and medication side effects. Based on these findings, the study concludes that a multidisciplinary strategy combining preoperative screening, optimized anesthetic management, and environmental interventions is essential to mitigate PSDs. By improving perioperative sleep quality, clinicians can significantly enhance patient satisfaction, reduce hospital stays, and promote rapid rehabilitation.