Boon B1*, De Praeter M2, Jentjens S3, van Heerden J4 1Department of Pediatrics, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium 2Department of Neurosurgery, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium 3Division of Nuclear Medicine, University Hospital Leuven, Leuven, Belgium 4Department of Pediatric Hematology and Oncology, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium
Corresponding Author: Bram Boon ORCID ID Address: Department of Paediatrics, Gasthuiszusters Antwerpen, Sint-Vincentius Ziekenhuis, Sint-Vincentiusstraat 20, 2018 Antwerp, Belgium. Received date: 15 October 2020; Accepted date: 07 November 2020; Published date: 14 November 2020
Citation: Boon B, De Praeter M, Jentjens S, van Heerden J. Focal Fibroadipose Overgrowth of the Forehead: A Case Report. Asp Biomed Clin Case Rep. 2020 Nov 14;3(3):234-40.
Keywords: Fibroadipose, Overgrowth, Adolescent Medicine
This article describes a rare case of isolated focal fibroadipose overgrowth of the forehead in a 15-year-old patient. Various overgrowth syndromes were considered in the differential diagnosis, including Proteus syndrome, facial infiltrating lipomatosis, and macrodystrophia lipomatosa. The diagnosis is primarily based on clinical presentation and imaging modalities. However, for academic and supporting diagnostic purposes a biopsy is advised, yet may not be in the best interest of the patient. Management was conservative with future perspective for surgical management after cessation of growth.
Key Clinical Message
Focal fibroadipose overgrowth can be caused by various overgrowth syndromes. Accurately diagnosing these syndromes is important, since there are differences in preferred therapeutic management and follow-up, including the need for cancer surveillance. In isolated, limited, benign focal fibroadipose overgrowth, the benefits of an invasive biopsy might be outweighed by the possible risks.