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Development of Febrile Seizures in Children with Iron Deficiency Anemia
Juan Pablo Gualdrón Moncada1*, Ana María Caballero Mieles2, Alexandra Paola Arrieta González3, Valeria Olarte Manjarres4, Natalia Andrea Cuevas Florez5, Laura Vanessa Molina Torres6, Diana Lisseth Rodriguez Paredes7, Erika Paola Ramirez Escobar3, Mayra Alejandra Santander Maury8
1Pediatric Resident, Corporación Universitaria Remington, Colombia
2General Physician, Universidad de Sucre, Colombia
3General Physician, Universidad Libre, Barranquilla, Colombia
4General Physician, Universidad El Bosque, Bogotá, Colombia
5General Physician, Universidad del Sinú - Seccional Cartagena, Colombia
6General Physician, Universidad de la Sabana, Colombia
7General Physician, Universidad Nacional de Colombia, Colombia
8General Physician, Universidad del Norte, Barranquilla
Corresponding Author: Juan Pablo Gualdrón Moncada ORCID iD
Address: Pediatric Resident, Corporación Universitaria Remington, Colombia.
Received date: 29 November 2021; Accepted date: 08 February 2022; Published date: 15 February 2022
Citation: Gualdrón Moncada JP, Caballero Mieles AM, Arrieta González AP, Manjarres VO, Cuevas Florez NA, Molina Torres LV, Rodriguez Paredes DL, Ramirez Escobar EP, Santander Maury MA. Development of Febrile Seizures in Children with Iron Deficiency Anemia. Asp Biomed Clin Case Rep. 2022 Feb 15;5(1):25-32.
Copyright © 2022 Gualdrón Moncada JP, Caballero Mieles AM, Arrieta González AP, Manjarres VO, Cuevas Florez NA, Molina Torres LV, Rodriguez Paredes DL, Ramirez Escobar EP, Santander Maury MA. This is an open-access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium provided the original work is properly cited.
Keywords: Iron Deficiency, Anemia, Iron, Febrile Seizure, Infant Population
A febrile seizure is a seizure that occurs in children with a temperature of 38 ºC or more, common in pediatric patients between the ages of 6 to 60 months without intracranial infections, metabolic disorder, or a history of seizures without fever. In 50% of children the first febrile seizure occurs at 2 years and in 90% before 3 years, anemia is also a frequent pathology in pediatric patients, in fact, the figures of the World Health Organization (WHO), point out that iron deficiency anemia attacks children under five years of age, occurring worldwide around 799 million, an average, in the last 10 years, of 42%. And in Latin America, the figure is 23%. Iron deficiency anemia can predispose to the development of febrile seizures because iron plays a crucial role in the transport of oxygen to all tissues, its deficiency also produces a dysfunction of myelination, tyrosine, and tryptophan synthesis hydroxylase, which are necessary for the release of neurotransmitters, therefore, if said neurotransmitters are not released, the brain synapse can be altered and lead to a seizure. Therefore, it is important and relevant to recognize these concepts and the intimate relationship between them, in addition to the risk factors that can trigger them, in order to promote the reduction of the risk of presenting these diseases in vulnerable groups such as pediatric patients.